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Understanding Stroke: Prevention, Recovery and the Importance of Strength Training

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I’d like to talk about something that’s become very personal to me: stroke. Recently, someone very close to me suffered a stroke, for which they are currently receiving very intensive treatment in the hope of making a recovery. The family, as you can imagine, has been terribly distressed by what has happened and we all hope for the best outcome. It’s a stark reminder of how fragile our health can be and how crucial it is to take proactive steps to protect it. This experience has driven me to write this article to increase our understanding of stroke, promote better awareness, and to encourage everyone to not take their health for granted.

What Is a Stroke?

A stroke occurs when blood flow to the brain is interrupted, either due to a blockage (ischemic stroke) or a rupture of a blood vessel (hemorrhagic stroke). In Australia, approximately 50,000 people experience a stroke each year, with around 472,000 Australians living with the effects of stroke, making it one of the leading causes of death and disability in the country (Stroke Foundation, 2021). The consequences can range from mild impairments to severe disability, depending on the area of the brain affected.

How to Prevent a Stroke

Prevention is always better than cure, right? Here are some key steps to lower your risk:

  1. Maintain a Healthy Diet: A diet rich in fruits, vegetables, whole grains, and lean proteins can reduce stroke risk by controlling blood pressure and cholesterol levels. The DASH (Dietary Approaches to Stop Hypertension) diet has been shown to significantly lower blood pressure (Mozaffarian et al., 2011).
  2. Regular Exercise: Engaging in at least 150 minutes of moderate aerobic activity weekly can decrease stroke risk by approximately 30-40% (Aune et al., 2016). Exercise helps maintain a healthy weight and reduces blood pressure.
  3. Control Blood Pressure: High blood pressure is the leading risk factor for stroke. Studies suggest that lowering blood pressure by as little as 5 mmHg can reduce the risk of stroke by 34% (Wang et al., 2014).
  4. Quit Smoking: Smoking increases the risk of stroke by 2 to 4 times. Quitting can significantly lower this risk over time (Roth et al., 2018).
  5. Limit Alcohol Consumption: Moderate alcohol consumption is defined as up to one drink per day for women and two for men. Excessive drinking increases stroke risk, with studies showing that heavy drinkers have a higher incidence of hemorrhagic stroke (Bagnardi et al., 2001).
  6. Manage Chronic Conditions: Conditions like diabetes and high cholesterol can elevate stroke risk. Effective management of these conditions is crucial for prevention (Gorelick et al., 2011).

If a Stroke Happens: Recovery Is Possible

Now, let’s talk about what happens if a stroke occurs. Recovery can be challenging, but it’s absolutely achievable. This is where strength training comes into play, particularly the concept of neuroplasticity—the brain’s ability to reorganize itself by forming new neural connections (Kleim & Jones, 2008).

After a stroke, rehabilitation often focuses on restoring lost functions, and strength training can be a key component. When you engage in strength training for the unaffected limb, there can be surprising benefits for the affected side, often referred to as cross-education.

Unilateral Strength Training and Cross-Education

What does this mean? Let’s say a stroke affects your right arm. If you focus on strength training your left arm, research shows that you may actually gain strength in your right arm as well, even though it isn’t directly being trained. A meta-analysis found that unilateral strength training can result in a strength increase of up to as high as 29% in the contralateral limb (Green & Gabriel, 2018). This occurs because the brain activates mirror neural pathways that can enhance strength in the affected side by stimulating the unaffected side.

Enhancing Physical Function and Quality of Life

Strength training doesn’t just aid in muscle recovery; it also improves overall physical function. For stroke survivors, regaining strength can lead to better mobility, increased independence, and improved quality of life. A study published in the Journal of NeuroEngineering and Rehabilitation found that strength training improved not only muscle strength but also functional abilities in stroke survivors (Lohse et al., 2014).

Moreover, engaging in strength training can boost mental well-being. Exercise releases endorphins, natural mood enhancers. For those recovering from a stroke, this can be invaluable for combating frustration or depression that often accompanies recovery.

Evidence-Based Interventions for Recovery

While strength training is a crucial part of rehabilitation, it’s not the only strategy that can enhance recovery. A multi-faceted approach incorporating various interventions has shown promising results.

  1. Dietary Interventions: Nutrition plays a significant role in recovery. Diets rich in omega-3 fatty acids (found in fish, flaxseed, and walnuts) have been associated with improved outcomes post-stroke (Gao et al., 2019). Additionally, antioxidants found in fruits and vegetables help combat oxidative stress in the brain, potentially aiding recovery.
  2. Exercise Beyond Strength Training: In addition to strength training, aerobic exercise has been shown to improve cardiovascular fitness, functional independence, and overall well-being in stroke survivors (Billinger et al., 2014). Activities like walking, cycling, and swimming can enhance cardiovascular health and aid in weight management, further reducing stroke risk.
  3. Cognitive Rehabilitation: Cognitive impairments are common after a stroke, and engaging in activities that stimulate the brain can be beneficial. Playing games like chess, puzzles, or memory games can enhance cognitive function and may facilitate neuroplasticity (Tao et al., 2020). Studies show that cognitive training can lead to improvements in attention, memory, and executive functions.
  4. Mindfulness and Stress Reduction: Stress can negatively impact recovery. Techniques such as mindfulness meditation and yoga can promote relaxation and improve psychological well-being. Research suggests that mindfulness-based interventions can reduce anxiety and depression in stroke survivors, contributing to a more positive recovery experience (Chung et al., 2019).
  5. Supplementation: Certain supplements have shown promise in stroke recovery. For instance, B vitamins (particularly B6, B12, and folic acid) play a role in homocysteine metabolism, and elevated levels of homocysteine are linked to an increased risk of stroke. Supplementing with these vitamins may help improve outcomes, especially in individuals with deficiencies (Schnyder et al., 2019).
  6. Community Engagement: Social support is vital for recovery. Participating in community activities, support groups, or engaging with family and friends can enhance emotional well-being. A study found that strong social ties are associated with better recovery outcomes in stroke survivors (Holt-Lunstad et al., 2010).
  7. Exercise Physiology: Working with an Exercise Physiologist can help stroke survivors regain the physical capacity and skills needed for daily living. They can develop personalized plans that incorporate various interventions to improve strength, balance, fitness, motor skills, cognitive function, and independence.
  8. Speech Therapy: If language or communication skills are affected, speech therapy is crucial. Therapists can employ various strategies to help patients regain their speech abilities and improve their quality of life.

A Comprehensive Approach to Recovery

Taking a holistic approach to stroke recovery is essential. Combining strength training with dietary changes, cognitive activities, mindfulness practices, and therapy can maximize recovery outcomes. Each element plays a crucial role in rebuilding strength, coordination, cognitive function, and emotional well-being.

Before starting any exercise or dietary program post-stroke, consulting with a healthcare provider or rehabilitation specialist is crucial. They can help tailor a program that’s safe and effective for your specific situation.

The Road Ahead

Recovering from a stroke is undoubtedly a journey, but with the right strategies—like preventative measures, strength training, neuroplasticity, and a multi-faceted approach to recovery—you can make significant strides. Whether you’re looking to prevent a stroke or navigate recovery, understanding the power of your body and brain can be a game-changer.

Remember, you’re not alone on this journey. Whether you’re supporting a loved one or navigating recovery yourself, there are resources and support communities there to help. Let’s embrace the science of strength training, nutrition, cognitive engagement, and overall wellness as powerful tools for a healthier, stronger future!

So, how about making sure you allocate some time to move today? Take a walk, get on your bike, do some light strength training, or even dance around to your favourite music, it all counts.

Take care of your health!


References

  • Aune, D., et al. (2016). “Physical Activity and the Risk of Stroke: A Meta-Analysis of Cohort Studies.” Stroke, 47(4), 1027-1035.
  • Bagnardi, V., et al. (2001). “Alcohol Consumption and the Risk of Stroke: A Meta-Analysis.” Stroke, 32(11), 2558-2564.
  • Billinger, S. A., et al. (2014). “Physical Activity and Exercise Recommendations for Stroke Survivors: A Statement for Healthcare Professionals from the American Heart Association/American Stroke Association.” Stroke, 45(8), 2535-2550.
  • CDC. (2021). “Stroke Facts.” Centers for Disease Control and Prevention. Retrieved from CDC.gov.
  • Chung, M. L., et al. (2019). “Mindfulness-Based Interventions for Patients with Cardiovascular Disease: A Systematic Review and Meta-Analysis.” Journal of Cardiovascular Nursing, 34(5), 447-458.
  • Gao, X., et al. (2019). “Omega-3 Fatty Acids and the Risk of Stroke: A Meta-Analysis.” Nutrients, 11(9), 2160.
  • Gorelick, P. B., et al. (2011). “Diagnosis and Management of Stroke Risk Factors.” Stroke, 42(8), 2363-2369.
  • Green, L. A., & Gabriel, D. A. (2018). The effect of unilateral training on contralateral limb strength in young, older, and patient populations: a meta-analysis of cross education. Physical Therapy Reviews23(4-5), 238-249.
  • Holt-Lunstad, J., et al. (2010). “Social Relationships and Mortality Risk: A Meta-analytic Review.” PLoS Medicine, 7(7), e1000316.
  • Kleim, J. A., & Jones, T. A. (2008). “Principles of Experience-Dependent Neural Plasticity: Implications for Rehabilitation After Brain Damage.” Journal of Speech, Language, and Hearing Research, 51(1), S225-S239.
  • Lohse, K., et al. (2014). “A Systematic Review of the Effect of Strength Training on Functional Recovery After Stroke.” Journal of NeuroEngineering and Rehabilitation, 11(1), 42.
  • Mozaffarian, D., et al. (2011). “Global Cardiovascular Disease and Diabetes: Current Status and Future Directions.” Journal of the American College of Cardiology, 58(14), 1404-1410.
  • Roth, G. A., et al. (2018). “Global and Regional Patterns in Cardiovascular Mortality from 1990 to 2013.” Global Heart, 13(3), 203-214.
  • Schnyder, G., et al. (2019). “The Role of B Vitamins in Stroke: A Review.” European Journal of Neurology, 26(4), 569-577.
  • Stroke Foundation. (2021). “Australia’s Stroke Statistics.” Retrieved from https://strokefoundation.org.au.
  • Tao, J., et al. (2020). “Cognitive Training Improves Cognitive Function in Stroke Survivors: A Systematic Review and Meta-Analysis.” Archives of Physical Medicine and Rehabilitation, 101(5), 949-958.
  • Wang, Y., et al. (2014). “Systolic Blood Pressure Reduction and Risk of Stroke: A Meta-Analysis.” Journal of the American College of Cardiology, 63(10), 1090-1098.
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12 Reasons Why Older Adults Need To Do Resistance Training Exercise: Part 2

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In part 1 of “12 reasons why older adults need to do resistance training exercise” I outlined some of the benefits to health that have been shown to occur as a result of partaking in regular resistance training exercise. The scientific evidence supporting the inclusion of resistance training as part of a healthy lifestyle is now indisputable. Whilst improvement of health is an obvious goal of many older athletes, it is the enhancement of sports performance that drives many in a quest to remain competitive, both against fellow competitors, but also – somewhat egocentrically – against their younger self. Even if you aren’t an elite masters athlete these benefits as outlined below can be truly life-changing.

Resistance training exercise remains an integral component of programs of most elite sportspeople. Increased maximal strength and power developed through the application of progressive resistance training has been shown to improve performance above and beyond that achieved by limiting training to sports specific training. This is now recognised by sports scientists, exercise physiologists, strength & conditioning experts and coaches.


strength training for over 60 female
Resistance Training Improves Older Athletes Performance (Picture: Pixabay)


Of particular note for older athletes is that the performance benefits may be even greater than that of younger elite athletes. One of the hallmark changes to occur with age is the progressive loss of strength with significant atrophy or loss of skeletal muscle playing a significant role. This fundamental biological change that occurs with ageing manifests in a gradual deterioration of physical function and performance.

However, there is compelling evidence that the trajectory of this decline is modifiable and can be attenuated by lifestyle factors. The data to support regular exercise as a key factor in preserving skeletal muscle and physical function is overwhelming. Resistance training is one of the very best methods currently available for older adults and masters athletes to stimulate the physiological processes required to increase myofibrillar protein synthesis rates, skeletal muscle hypertrophy and muscular strength. These skeletal muscle adaptations lie at the core of why this type of exercise improves the functional performance of older adults and athletic performance of masters athletes.

The following 6 compelling reasons explain why resistance exercise should be included in all training programs of older adults where enhanced performance – for activities of daily living or sporting – are desired.


strength training for over 60 female
Resistance training and bone strength (Picture: Pixabay)


Enhance skeletal health. Stronger bones can handle greater training loads and transfer muscular forces more effectively and efficiently. Bone mineral density (BMD) decreases as we age however this can be slowed by regular physical activity and appropriate nutrition. Risk of musculoskeletal injury is increased when bone strength is decreased with age, especially during falls that can cause catastrophic consequences for some.

Resistance training has been shown to be quite a potent stimulus for improving bone mineral density. Some evidence suggests that plyometric-type or jumping activities also provide an excellent training method to stimulate significant and positive bone adaptation which yields increased BMD and therefore stronger bones.

Masters cyclists as a group are unfortunately at an elevated risk of reduced BMD (weaker bones) due to the non-weight bearing nature of cycling. It is strongly recommended that all masters cyclists – in fact, all cyclists – should perform adjunctive resistance exercise in their training program (see links 1, 2, 3, 4 & 5).


strength training for over 60 female
Resistance Training And Skeletal Muscle (Picture: Google Images)


Maintain or increase lean body mass (skeletal muscle). Remember muscle is critical to both speed and endurance performance. From age 50 onwards muscle loss accelerates but there is a substantial amount of evidence that this is exacerbated by increased sedentarism (inactivity). Resistance training attenuates muscle mass loss.

Ageing is accompanied by reduced muscle mass and this has been mainly attributed to type II muscle fibre atrophy or reduction in size. It is unlikely that there is substantial muscle fibre loss however this remains to be elucidated. In older adults that have demonstrated substantial lean body mass loss and type II muscle fibre atrophy, prolonged resistance training has demonstrated significant increased muscle mass and this was shown to occur exclusively in type II muscle fibres. Nonetheless, some research has shown both type I and type II muscle fibre hypertrophy so more data is required to ascertain whether such things as age, gender, training status and training program parameters, affect muscle fibre changes and responsiveness to resistance training exercise (see links 1, 2, 3, 4, 5, 6).


Increased muscular strength, power and speed. Research investigating the effects of progressive resistance training programs demonstrate that muscle strength, power and speed improve, and in many case, quite impressively. In fact, even in nonagenarians, skeletal muscle strength and functional mobility assessed by a gait velocity test improved dramatically (>170% and 48% increase, respectively) after only 8 weeks of resistance training.

As mentioned above, the significant atrophy that occurs with age in fast-twitch type II muscle fibres, directly impacts performance of activities that require speed. Resistance training can reverse some of this decline, restore some of the lost contractile protein of these critical muscle fibres, increase maximum skeletal muscle strength and therefore elicit substantial improvements in movement speed of various specific sporting skills.

Older athletes that are avoiding or not adjusting their program to allow a little time to perform some resistance training exercise are missing out on some incredible benefits (see links 1, 2, 3, 4, 5).


strength training for over 60 female
Resistance Training And Body Fat


Lose body fat and get leaner. As outlined above, skeletal muscle mass decreases significantly from age 50 with concomitant decreases in resting metabolic rate (RMR). RMR is the largest component of total daily energy expenditure (TDEE) accounting for 60-80%. Whilst reductions in muscle mass account for a significant proportion of the accommodating changes in RMR, decreasing organ mass and decreases to specific metabolic rates of individual tissues also contribute to the decrease in RMR.

These age-related changes in RMR reduce TDEE. This may contribute to increased adiposity as we grow older given that energy intake to maintain body mass decreases proportionally to the degree of reduction in RMR and TDEE. In other words, if dietary habits and energy intake remains constant over time but RMR and TDEE decrease subsequent to the loss of skeletal muscle, positive energy balance may ensue and fat mass may therefore naturally increase.

Resistance training is well known for stimulating muscle hypertrophy or increasing skeletal muscle mass and has been shown to elicit reductions in fat mass in obesity during ad libitum diets. In contrast, aerobic exercise-induced weight loss consistently leads to reductions in lean body mass and RMR which may make the propensity of rebound fat gain more likely.

Inclusion of resistance training exercise in programs of older athletes or non-athletes doesn’t guarantee that there will be body fat loss (nutrition and diet obviously play a key role) but it certainly makes weight management easier and supports weight loss efforts if modifying the diet in an attempt to get leaner. Much of the research that has investigated the utility of resistance training in older adults demonstrates that it is a very effective fat loss strategy when performed with other lifestyle-based interventions aimed at improving physical function and body composition (see links 1, 2, 3, 4, 5).


strength training for over 60 female
Resistance Training And Endurance Performance (Picture: Google Images)


Improves endurance. Resistance training that is designed to increase muscle strength and power has been shown to improve endurance performance. More evidence exists to support such exercise in younger adult athletes as there has been limited research exclusively focused on older athletes.

Nonetheless, the research completed to date is strongly suggestive that resistance training enhances endurance in older athletes and non-athletes. A study conducted in 2010 demonstrated that strength training consisting of 10 sets of 10 repetitions of 1RM load, 3 minutes rest between each set, 3 times/week, increased both knee extensor maximal voluntary contraction torque and cycling efficiency. It is reasonable to postulate that had they utilised a program that incorporated more compound, complex, multi-jointed exercises such as squats and deadlifts – such that all major lower body muscle groups were strengthened – significantly greater cycling economical benefit would have been elicited.

When masters endurance runners were studied after following a resistance training program designed to increase maximal strength (4 sets of 3-4 repetitions at 85-90% of 1RM, two times per week), a significant improvement in running economy at marathon pace (6.1%) and dynamic leg strength (16.3%) was achieved.

It is proposed that the following training adaptations may facilitate endurance performance improvement:

  • the delayed use of the fast-twitch type II muscle fibers;
  • enhanced neuromuscular efficiency;
  • increased proportion of more fatigue-resistant fast-twitch type IIa fibres;
  • improved musculo-tendinous stiffness (see links 1, 2, 3).

strength training for over 60 female
Resistance Training and Injury Prevention (Picture: Google Images)


Reduce injury risk. Regularly performed resistance exercise can minimize the musculoskeletal alterations that occur during ageing. It may also contribute to the health and well-being of the older population.

There is strong evidence that suggests such exercise can prevent and control the development of several chronic musculoskeletal diseases. Improvement of physical fitness, function, and independence in older people, plus successful management of musculoskeletal disorders, results in dramatic improvements in quality of life.

Stronger muscles, bones, connective tissue, ligaments and tendons mean our limbs and joints are more able to handle the rigours of training, competing and activities of daily living (see links 1, 2, 3, 45).

In conclusion, based on the 12 reasons that I have explored which demonstrate profound benefits to both the health, functional and sporting performance of older athletes and non-athletes, resistance training is a must-do and should be a pivotal component of any exercise program.

To read “12 reasons why older adults need to do resistance training exercise: part 1” that explores the health-related benefits in older adults see here.


For local Townsville residents interested in FitGreyStrong’s Exercise Physiology services or exercise programs designed to achieve the mentioned benefits or to enhance athletic performance, contact FitGreyStrong@outlook.com or phone 0499 846 955 for a confidential discussion.

For other Australian residents or oversees readers interested in our services, please see here.


Disclaimer: All contents of the FitGreyStrong website/blog are provided for information and education purposes only. Those interested in making changes to their exercise, lifestyle, dietary, supplement or medication regimens should consult a relevantly qualified and competent health care professional. Those who decide to apply or implement any of the information, advice, and/or recommendations on this website do so knowingly and at their own risk. The owner and any contributors to this site accept no responsibility or liability whatsoever for any harm caused, real or imagined, from the use or distribution of information found at FitGreyStrong. Please leave this site immediately if you, the reader, find any of these conditions not acceptable.


© FitGreyStrong

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Regular Exercise Doesn’t Promote Weight Loss: Fact or Fiction?

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Several years ago researchers and authors Malhotra, Noakes & Phinney published an article in the British Journal of Sports Medicine titled:

“It is time to bust the myth of physical inactivity and obesity: you cannot outrun a bad diet” (see here)

This created quite a storm in several fields of scientific research including many fitness and nutrition blogs. It was lambasted by some though as inaccurate and misleading – just Google the title of the article and you’ll understand what I mean. Essentially, their article claimed that regular physical activity does not promote weight loss and that excessive consumption of carbohydrates, in particular, sugar, is the primary cause of the obesity epidemic. Whilst excessive sugar consumption has played an important role in exacerbating the obesity crisis, it would be naive and short-sighted to suggest that this is the be-all and end-all in explaining society’s current predicament.

More recently Julia Belluz and Javier Zarracina published (April 2016) an article at Vox titled:

“Why you shouldn’t exercise to lose weight, explained with 60+ studies” (see here)

This article posits that exercise is unhelpful for weight loss and makes very similar claims to the Malhotra et al. paper. Of course, the real question is, are these claims valid? Could it really be true that weight loss is not facilitated by increasing daily energy expenditure and exercise? I think the answer to these questions are not black or white. My main concern with the articles mentioned above is that they are rather myopic, polarising and do not provide a fair and balanced assessment of the current evidence.

Instead, the evidence published to date demonstrates that ‘our’ increasing waistlines are closely related – but not confined to – the interaction of the following 3 factors. Firstly, the sum total of all physical movement performed whilst awake has substantially decreased over the last 50 years. Secondly, activities of a sedentary nature have dramatically increased. What are you doing right now? Thirdly, total energy intake over the last 50 years has continued to increase over and above total daily energy expenditure requirements. If movement levels are low and energy intake high – irrespective of where the excess is derived from – body weight, body fat and BMI will naturally increase. But does increasing physical activity levels via a formalised exercise program and/or non-exercise based physical activities (e.g. leisure time movement, domestic chores/activities) facilitate weight loss by increasing total daily energy expenditure? The answer to this is yes and no.

Today I want to focus on the evidence that was accessible following a  brief Google Scholar search that supports exercise as well as other non-exercise increases in daily physical movement as being promoters of weight loss. For anybody not familiar with Google Scholar (https://scholar.google.com.au), it is a search engine by Google that searches for only published, peer-reviewed journal-based research and consequently provides information that is evidence-based rather than ‘opinion-based’ which is largely what would be accessed via Google, Yahoo or any other search engine. So, what did I find?

One of the more interesting pieces of research that directly contradicts the article by Malhotra and co. is that written by Church et al. (2011). They concluded that over the last 50 years in the U.S., daily occupation-related energy expenditure was estimated to have decreased by more than 100 calories per day, and this reduction in energy expenditure could account for a significant portion of the increase in mean U.S. body weights for women and men. What this would suggest is that rather than increased obesity rates being caused exclusively by too many carbs or too much sugar, as argued by the “you can’t outrun a bad diet” article, the current problem has been driven by large reductions in energy expenditure due to changes to occupation-related physical movement. In other words, we have transitioned from jobs that are active and require a lot of physical movement to jobs now that have most of us sitting on our backsides for hours on end.

Work places changes to physical activity
Doing this all day can’t be helpful


Previous reports based on estimated caloric consumption from food production and food disappearance (food waste) estimates have concluded that increased caloric consumption could account for most, if not all, of the weight gained at a population level in the U.S. Nonetheless, a recently validated differential equation model was used to identify a conservative lower bound for the amount of food waste in the U.S. (Hall et al. 2009). This analysis determined that prior estimates of national food waste were grossly underestimated; indicating that the national average caloric intake was much lower than previously estimated. As such, these results and those of Church imply that increased caloric intake or for that matter, increased sugar consumption, cannot solely account for the observed trends in national weight gain in the US.

The following is a summary of some of the research that has been published investigating whether obesity is related to physical inactivity and what effect increased physical activity has on obesity risk and management.

1. Banks et al. (2010) reported that: “Obesity increases with increasing screen-time, independent of purposeful physical activity.”

2. Goodpaster et al. (2010) found that: “Among patients with severe obesity, a lifestyle intervention involving diet combined with initial or delayed initiation of physical activity resulted in clinically significant weight loss and favourable changes in cardiometabolic risk factors.” In the group where physical activity was delayed, the addition of such physical activity promoted greater reductions in waist circumference and hepatic fat content.

3. Banks et al. (2011) showed that: “Domestic activities and sedentary behaviours are important in relation to obesity in Thailand, independent of exercise-related physical activity. In this setting, programs to prevent and treat obesity through increasing general physical activity need to consider overall energy expenditure and address a wide range of low-intensity high-volume activities in order to be effective.”

4. Villareal et al. (2011) demonstrated that: “…in obese older adults a combination of weight loss and exercise provides greater improvement in physical function than either intervention alone.”

5. McGuire & Ross (2012) reported that: “…light physical activity, incidental physical activity and sedentary behaviour were not associated with abdominal obesity amongst inactive men and women whereas moderate-to-vigourous physical activity predicted lower visceral adipose tissue.”

6. The study by Fan et al. (2013) was: “…to test if moderate-to-vigorous physical activity (MVPA) in less than the recommended ≥10-minute bouts related to weight outcomes.” Both higher-intensity short bouts and long bouts of physical activity related to lower BMI and risk of overweight/obesity whereas neither lower-intensity short bouts nor long bouts related to BMI or risk of overweight/obesity. They concluded that: “The current ≥10-minute MVPA bouts guideline was based on health benefits other than weight outcomes. Our findings showed that for weight gain prevention, accumulated higher-intensity PA bouts of <10 minutes are highly beneficial, supporting the public health promotion message that ‘every minute counts’.”

7. Cleland et al. (2014) found that: “High sitting and low activity increased obesity odds among adults. Irrespective of sitting, men with low step counts had increased odds of obesity. The findings highlight the importance of engaging in physical activity and limiting sitting.”

8. Jakicic et al. (2014) concluded that moderate-to-vigorous physical activity (MVPA > 10) of 200-300 min per week, coupled with increased amounts of low-intensity physical activity (LPA), are associated with improved long-term weight loss. Interventions should promote engagement in these amounts and types of physical activity.

9. Murabito et al. (2015) discovered that moderate-to-vigorous physical activity (MVPA) as measured by accelerometry was associated with less visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) and better fat quality as assessed by multi-detector computed tomography. With increasing MVPA, there was a concomitant decrease in VAT. Higher levels of MVPA were associated with higher SAT fat quality, even after adjustment for SAT volume. They concluded that:

“MVPA was associated with less VAT and SAT and better fat quality.”

10. Mekary et al (2015) reported that: “….over 12 years long-term weight training is associated with less waist circumference increase, whilst moderate-to-vigorous aerobic activity was associated with less body weight gain in healthy men.”

11. Hume et al. (2016) concluded that: “….counter to the energy surfeit model of obesity, results suggest that increasing energy expenditure may be more effective for reducing body fat than caloric restriction, which is currently the treatment of choice for obesity.”

12. Myers et al. (2016) suggests that there exists clear associations among objective measures of physical activity, sedentary behaviour, energy expenditure, adiposity and appetite control. They produced data that indicates strong links between physical inactivity and obesity with this relationship likely to be bidirectional.

13. Wu et al. (2017) tested 12-weeks of low- and high-intensity exercise training in Mexican-American and Korean premenopausal overweight/obese women. Results showed that such exercise reduced body mass index, body fat percentage, fat mass and visceral adipose tissue with concurrent increases in lean mass.

14. Quist et al. (2018) examined the effects of 6-months of active commuting and leisure-time exercise on fat loss in women and men who were overweight or obese. Clinically meaningful fat loss of over 4 kilograms was elicited. Vigorous intensity exercise was shown to be more effective in reducing body fat versus moderate intensity exercise.

15. Stoner et al. (2019) concluded that the findings of their meta-regression “lend support to the use of exercise prescription for promoting weight loss and improving health outcomes in adolescents with overweight/obesity.”

16. Zhang et al. (2020) found that 12-weeks of intense exercise (without concurrent nutritional intervention, i.e. ‘put on a diet’) significantly improved cardiometabolic parameters (i.e. fasting blood glucose) and decreased weight, total percent body fat, whole-body fat mass, android, gynoid, and trunk fat mass, abdominal subcutaneous fat and abdominal visceral fat. Reductions of over 15 cm² of abdominal visceral fat were achieved in just 3 months!

17. Berge et al. (2021) produced clinically significant weight loss in people with severe obesity despite the study having no specific focus on body weight reduction. The group that performed moderate‐intensity continuous training combined with high‐intensity interval training lost an average of 5 kilograms in 24-weeks.

Weight training, older adults and quality of life
Staying strong as we age is critical to health


What does this research tell us?

Quite a lot I would say. Of particular note is that this only represents a very small sample of the evidence that directly counters the claim that widespread societal levels of physical inactivity have little to do with burgeoning obesity rates. What is more, it crystallizes just how contentious Malhotra, Noakes & Phinney’s editorial was. Exclusively assigning blame for the obesity epidemic to the excessive intake of sugar is not supported, I believe, by the current evidence. The dramatic reductions in the sum total of all physical activity accumulated during the day appears to account for a substantial amount of the increased weight seen in recent decades.

Firstly, there is a substantial amount of research which demonstrates that sedentary behaviours, sitting time and low physical activity levels manifestly increase one’s risk of becoming overweight or obese. Secondly, moderate-to-vigourous physical activity compared to light physical activity has been shown to be associated with less visceral and subcutaneous adipose tissue, impacts positive effects on fat quality, is related to lower BMI, lowers risk of overweight/obesity, prevents weight gain following weight loss, promotes greater reductions in waist circumference and produces favourable changes in cardio-metabolic risk factors.

So to conclude, my Google Scholar search unveiled that there is a large body of evidence that demonstrates that there may be no myth to bust regarding obesity and physical inactivity or foundation to suggesting that physical activity plays no role toward promoting weight loss. Others have been critical of this line of thinking too, in particular Dr Steven Blair, so I would suggest that if you wanted to read further on this here would be a good place to start.

My next article will explore the evidence that exercise does not assist weight loss in all exercisers due to various compensatory mechanisms (see here). Until then, stay active, keep moving and don’t forget to include some resistance exercise in your week.


For local Townsville residents interested in FitGreyStrong’s Exercise Physiology services or exercise programs designed to improve health, physical function and quality of life or to enhance athletic performance, contact FitGreyStrong@outlook.com or phone 0499 846 955 for a confidential discussion.

For other Australian residents or oversees readers interested in our services, please see here.


Disclaimer: All contents of the FitGreyStrong website/blog are provided for information and education purposes only. Those interested in making changes to their exercise, lifestyle, dietary, supplement or medication regimens should consult a relevantly qualified and competent health care professional. Those who decide to apply or implement any of the information, advice, and/or recommendations on this website do so knowingly and at their own risk. The owner and any contributors to this site accept no responsibility or liability whatsoever for any harm caused, real or imagined, from the use or distribution of information found at FitGreyStrong. Please leave this site immediately if you, the reader, find any of these conditions not acceptable.
© FitGreyStrong
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Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults – part 1

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On a global scale, the number of people over 60 yr is expected to more than double from 841 million in 2012 to more than 2 billion by 2050. This change in demographics will have profound implications for many aspects of life (Thomson et al. 2016). Furthermore, Government bodies worldwide will be faced with considerable challenges related to ageing policy and how best to deal with this new reality.

ageing, loss of muscle mass, strength, sarcopenia
Courtesy @LeighBreen PhD (Twitter): Sarcopenia presentation


Of the many things that occur during the ageing process one of the most obvious signs is the loss of skeletal muscle mass and strength, with decrements in physical function and potential predisposition to disability. In academic speak, this is known as sarcopenia. The research and interest in this area has been gradually increasing as evidenced by the below graph that shows – since the term sacropenia was first coined in 1989 – a massive increase has occurred. To enhance functional physical capacity and reduce disability into older age, it is therefore critical to develop strategies that facilitate the attenuation of skeletal muscle mass and strength. With more than 30 years of scientific evidence to show that exercise – and, more specifically, resistance training – as both very effective and safe methods to maintain skeletal lean muscle tissue mass and strength (see here and here), current recommendations strongly advocate this form of exercise for older adults.

Interestingly, gains in skeletal lean muscle tissue and muscular strength may be potentiated through the application of appropriate nutritional strategies and in particular increased protein intake. A recent meta-analysis by Cermak and colleagues (2012) reported ~35% greater enhancement in muscle mass and strength can be achieved in older adults undertaking resistance training who consumed at least 1.2 g/kg of body weight/d of protein through supplementation or diet compared with other control groups that were either non-protein, lower protein diet or exercise training with no nutrition co-intervention. Thus, protein quality or source may further augment the effect of the resistance training stimulus by eliciting a greater stimulatory effect on muscle protein synthesis. Dairy protein compared to soy protein has been shown to be more effacacious post-exercise in stimulating increases in lean mass in young healthy males. In older adults though this response to resistance training and increased protein intake may be blunted which necessitates that higher doses of protein are required to bring about an increase.

The aim of the study under review for this article was to determine whether increased dairy or soy protein intake combined with resistance training improved strength gains in older adults.

Soy protein, strength, muscle mass, testosterone
Does Soy Protein Suppress Strength Gains?


Researchers recruited one hundred and ninety two older adults (age, 50-79 yr; BMI, 20-35 kg/m²) by public advertisement. Participation was allowed if they were physically active but not engaged in formal exercise. Those that meet the inclusion criteria undertook a resistance training program for 12 weeks. Randomisation to one of three experimental diets was performed:

  1. High dairy protein diet (HP-D)
  2. High non-dairy (soy) protein diet (HPeS)
  3. Usual protein diet (UP).

DIET: Each diet was isocaloric and low-fat (30% fat, <8% saturated fat) and aimed to maintain energy balance. The diets provided ~1 g/kg of body weight/d of dietary protein, mainly from lean meat sources. HP-D including additional dairy protein of ~27 g per day in the form of a shake (475 g Devondale Smart reduced fat milk, 200 g Nestle Soleil diet no fat yoghurt & 20 ml Bickfords vanilla milk mix syrup). The HP-S providing in the form of a shake – 300 g So Good reduced fat soy milk, 100 g Kingland soy yoghurt, 20 g Nature’s Way instant natural protein powder & 15 g poly-joule – which added an extra ~27 g of soy protein. Protein intake was distribtuted evenly across the day with the three main meals providing >20 g per feed; this is consistent with best practice for optimising muscle protein synthesis in older adults. Following resistance training sessions participants consumed the appropriate additional foods immediately after training and that represented the main meal of that day. Participants were supplied with key foods specific to their allocated diet for the duration of the study to facilitate adherence. Energy and macronutrient intakes from daily food checklists were analysed to monitor food intake and dietary compliance.

Strength training and ageing
Resistance training: a key component of healthy ageing?


RESISTANCE TRAINING: All subjects participated in a whole body resistance training program three days per week on non-consecutive days for 12 weeks and the principles of progressive overload were applied.  Five exercises on weight stack pin loaded machines were performed: leg press, chest press, knee extension, lat pull down and leg curl, and seated bent knee hip flexions. Trainees started with one set x 8 repetition maximum (RM; maximum weight lifted for eight repetitions), this was maintained until individuals could perform three sets of 12 repetitions and then the load was increased. This cycle was repeated again for the duration of the trial. Assessment of muscle strength, body composition, physical function and quality of life was conducted at baseline and 12 weeks. All exercise training was completed in the research gymnasium at the University of South Australia under the supervision of gymnasium staff.

Assessment of muscle strength using handgrip, isokinetic dynamometry and 8RM was completed. The leg press, chest press, knee extension, lat pull down and leg curl were tested with 8RM and a summed total 8RM for all exercises was recorded  Dominant handgrip strength was measured using hydraulic handgrip dynamometer and isometric strength of the knee extensor muscles of the right leg was assessed using an isokinetic dynamometer.

resistance training slows down aging
You don’t have to lift weights to do resistance training


RESULTS: 83 participants completed the intervention being adherent to both diet and resistance training protocols. HP-D and HP-S had higher protein intakes compared with UP (HP-D 1.41 ± 0.14 g/kg/d, HP-S 1.42 ± 0.61 g/kg/d, UP 1.10 ± 0.10 g/kg/d; P < 0.001 treatment effect). Baseline characteristics, compliance with the intakes of the additional protein foods and adherence to the resistance training program in those that meet all relevant study protocols was not different between groups.

Increase in muscular strength as ascertained by total 8RM was significantly less in HP-S compared with HP-D and UP (HP-D 92.1 ± 40.8%, HP-S 63.0 ± 23.8%,UP 92.3 ± 35.4%; P=0.002 treatment effect). 8RM percent improvement in leg press was much greater in HP-D and UP compared with HP-S (HP-D, 136.8 ± 88.2%; HP-S, 64.8 ± 35.2%; UP, 135.0 ± 62.0%; P < 0.001). For most other exercises, 8RM was not signficantly different for each diet group. Total training volume over the 12 weeks was not different between groups.

Weight, waist circumference and total body fat decreased and lean mass and the distance covered during the 6 min walk test increased significantly increased with no difference between diets. As expected absolute protein intake (g) and relative protein intake (per kg body weight) were different with HP-D and HP-S greater than UP. Dairy protein in HP-D was significantly greater compared with both HP-S and UP with the amount of non-dairy protein in HP-S significantly greater compared with both HP-D and UP.

DISCUSSION: This study has demonstrated that 12 weeks of progressive resistance training exercise in healthy older adults did not provide any additional benefit for improvements in strength, body composition, physical function, or quality of life when additional protein from either dairy or soy is compared to usual (lower) protein intake. Perhaps of more significant interest is that results suggested that increased soy protein intake attenuated improvements in muscular strength. I am going to publish this article before it is entirely finished as I believe this is important research for those interested in this area and facilitating discussion on this topic should start now.

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Stay strong and prosper


Over the next week or so I will be posting a part 2 in relation to this study as there is a lot more to explore. For example, why did the authors fail to acknowledge or discuss the fact that the attentuated strength improvement in the HP-S was confined exclusively to the leg press exercise? For all other exercises, no difference for dietary influence on strength improvement was found. Whilst not a criticism, it seems rather odd that whey protein was not included as one of the intervention dietary arms of the study. The evidence for whey protein augmenting the development of strength and facilitating the accretion of lean muscle mass from resistance training is well documented. Comparing this with the other diets would have provided some interesting insights into whether there are any further benefits of whey protein to older adults. Finally, one thing that does disappoint me about many of the studies that investigate the efficacy and safety of resistance training in older adults is the reliance on exercises that are machine-based.

CONCLUSION: Increased soy protein intake attenuated gains in muscle strength during resistance training in older adults compared with increased intake of dairy protein or usual protein intake.

Look out for part 2 (see here) titled “Does Soy Protein Really Inhibit Resistance Training Induced Strength Gains In Older Adults?” where I will discuss some of the things I mentioned above in more depth and some possible mechanisms of action as to why soy protein may or may not suppress strength gains from resistance training.

Post-script: Following further analysis and publication of part 2 of this blog, I wrote a letter to the Editor of Clinical Nutrition Journal outlining some of the, what I believed, flaws regarding the interpretation of the results of this trial. Upon peer review this was accepted for publication and can be found here. If you are unable to access this correspondence and the authors reply to my letter, please contact me and I should be able to assist. 

References

Cermak et al. (2012) Protein supplementaiton augments the adaptrive response of skeletal muscle to resistance-type exercise training: a meta-analysis Am J Clin Nutr 96: 1454- 64.

Thomson et al. (2016) Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults: A randomized controlled trial. Clinical Nutrition. 35: 27-33

Wilson, SA (2016) Comment on: Muscle strength gains during resistance exercise training are attenuated with soy compared with dairy or usual protein intake in older adults: A randomized controlled trial. Clinical Nutrition. 35(6):1575-1576


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